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A chemiluminescent metalloimmunoassay based on copper‐enhanced gold nanoparticles for quantification of human growth hormone

Authors:: Foroozan Hasanpour, Taghi Khayamian, Ali Ensafi, Hamidreza Rahmani, Behzad Rezaei
Publication date: 2012/9/1
Journal name: Luminescence
 
ABSTRACT A chemiluminescence (CL) immunoassay was developed to determine human
growth hormone (hGH) based on copper-enhanced gold nanoparticles. In this method, gold
nanoparticles were deposited on polystyrene wells for adsorption of human growth
antibodies as well as catalyst for reducing of copper ions from the copper enhancer solution.
The reduction of copper ions was prevented where the gold nanoparticles were covered by
the antibody–antigen immunocomplex. The deposited copper on Au nanoparticles was ...

 

Journal Papers
Month/Season: 
September
Year: 
2012

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