A novel sensitive DNA–biosensor for detection of a carcinogen, Sudan II, using electrochemically treated pencil graphite electrode by voltammetric methods

Authors Ali A Ensafi, Behzad Rezaei, Maryam Amini, Esmaeil Heydari-Bafrooei

Publication date: 2012/1/15

Journal name: Talanta

Volume: 88

Pages: 244-251

Publisher: Elsevier

A simple and inexpensive methodology was used to develop a novel electrochemical
sensor for the determination of Sudan II. The interaction of Sudan II with salmon sperm ds-
DNA on the surface of salmon sperm ds-DNA-modified pencil graphite electrode (PGE) and
in solution phase was studied, using differential pulse voltammetry. The difference between
adenine and guanine signals of the ds-DNA after and before interaction with Sudan II was
directly proportional to Sudan II concentration, which used for quantitative inspections. ...