PVC Membrane Selective Electrode for Determination of Isoproterenol Based on Naphthylethyl Dihydrochloride–Tetraphenyl Boranuide, Ali A. Ensafi, A.R. Allafchian, Behzad Rezaei, Anal. Bioanal. Electrochem., 2015, 7(5), 569-581.
A new coated–wire membrane selective electrode as a potentiometric sensor was
developed for the determination of isoproterenol. Naphthylethylenediamine dihydrochloride–
tetraphenyl boranuide ion–exchangers was used as an electroactive material on the
membrane. The sensor displays a linear response with a slope of 56.9 mV decade –1 for
isoproterenol in the concentration range of 1.0×10 –2 –5.0×10 –6 mol L –1 , with detection limit of
3.3×10 –6 mol L –1 . The potentiometric response is independent of the pH of the solution in the
pH range of 3.0 – 6.8. Selectivity coefficient data for some common inorganic cations, sugars
and components of the mixed drugs were investigated and showed negligible interference.
The response time of <5 s was displayed. The sensor can be used for more than 2 months
without any considerable divergence in the potential. For the practical purposes, the
efficiency of the method in the extraction and determination of isoproterenol for biological
fluids such as urine and blood serum samples was evaluated without any special