For Better Performance Please Use Chrome or Firefox Web Browser

A sensitive nanocomposite-based electrochemical sensor for voltammetric simultaneous determination of isoproterenol, acetaminophen and tryptophan

A sensitive nanocomposite-based electrochemical sensor for voltammetric simultaneous determination of isoproterenol, acetaminophen and tryptophan

 
 
 

Highlights

 

A novel nanocomposite paste electrode was used for electrooxidation of isoproterenol.

The sensor resolved the overlap response of isoproterenol acetaminophen and tryptophan.

This sensor was used for the determination of above compounds in real samples.

 


Abstract

The electrooxidation of isoproterenol (ISPT), acetaminophen (AC) and tryptophan (Trp) and their mixture has been studied using an 8,9-dihydroxy-7-methyl-12H-benzothiazolo[2,3-b]quinazolin-12-one modified multiwall carbon nanotubes paste electrode (DMBQ-MCNTPE). The novel sensor exhibited potent and persistent electron mediating behavior followed by well separated oxidation peaks towards ISPT, AC and Trp with activation over-potential. The peak currents were linearly dependent on ISPT, AC and Trp concentrations using square wave voltammetry (SWV) method in the range of 0.04–400, 5.0–500, and 10.0–800 μmol L−1, with detection limits of 0.009, 1.0, and 4.0 μmol L−1, respectively. The modified electrode was used for the determination of ISPT, AC and Trp in biological and pharmaceutical samples.

 

Journal Papers
Month/Season: 
May
Year: 
2014