Authors: Ali A ENSAFI, Elaheh KHODDAMI, Behzad REZAEI

Publication date: 2013/3

Journal name: Analytical sciences: the international journal of the Japan Society for Analytical Chemistry

Volume: 29

Pages: 303

Atorvastatin (Scheme 1) is a member of a drug class known as statins, used for lowering
blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory
and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase,
an enzyme found in liver tissue that plays a key role in the production of cholesterol in the
body. The primary use of atorvastatin is for treating of dyslipidemia and preventing
cardiovascular disease. 1 Atorvastatin and other statins are associated with anecdotal ...