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- فارسی
Determination of glutathione in hemolysed erythrocyte by flow injection analysis with chemiluminescence detection
Authors: AA Ensafi, T Khayamian, F Hasanpour
Publication date: 2008/9/10
Journal name: Journal of pharmaceutical and biomedical analysis
Volume: 48
Pages: 140-144
Publisher: Elsevier
In this work, a new sensitive method is introduced for analysis of glutathione at trace levels
in blood samples. The method is based on the effect of glutathione on the
chemiluminescence signal of the oxidation of luminol by sodium periodate in basic solution.
The influence of chemical and manifold variables on the sensitivity was studied. At the
optimized conditions, the linear range for the determination of glutathione was 1.0× 10− 8 to
1.0× 10− 5molL− 1 with the detection limit (3σ) of 8× 10− 9molL− 1. The relative standard ...
in blood samples. The method is based on the effect of glutathione on the
chemiluminescence signal of the oxidation of luminol by sodium periodate in basic solution.
The influence of chemical and manifold variables on the sensitivity was studied. At the
optimized conditions, the linear range for the determination of glutathione was 1.0× 10− 8 to
1.0× 10− 5molL− 1 with the detection limit (3σ) of 8× 10− 9molL− 1. The relative standard ...
Journal Papers
Month/Season:
September
Year:
2008