Electrochemical Sensing of Flutamide Contained in Plasma and Urine Matrices Using NiFe2O4/rGO Nanocomposite, as an Efficient and Selective Electrocatalyst

Ali Asghar Ensafi, Bahareh Mandian Talkhooncheh, Navid Zandi-Atashbar, Behzad Rezaei,

https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.100...

Abstract: In this article, we report on the synthesis and new employment of magnetic nickelferrite oxide nanoparticles decorated reduced graphene oxide (NiFe2O4/ rGO) to electrochemically sensing of flutamide. The preparation of this electrocatalyst was first assessed using various analytical instrumental techniques including FTIR spectroscopy, X-ray diffraction spectroscopy, energydispersive X-ray spectroscopy, and field emission scanning and transmission electron microscopy. Besides, its electrochemical performance was investigated utilizing some electrochemical methods such as cyclic and differential pulse voltammetry, and also electrochemical impedance spectroscopy. The findings of this research are especially relevant for sensing flutamide in aqueous and biological samples. At the optimized conditions, the electrochemical sensor showed a linear range of 0.24–40.0 μmolL,the detection limit of 0.05 μmolL.

Keywords: NiFe2O4 · Reduced graphene oxide · Nanocomposite · Flutamide · Electrocatalyst