Authors: AA Ensafi, T Khayamian, F Hasanpour

Publication date: 2008/9/10

Journal name: Journal of pharmaceutical and biomedical analysis

Volume: 48

Pages: 140-144

Publisher: Elsevier

In this work, a new sensitive method is introduced for analysis of glutathione at trace levels
in blood samples. The method is based on the effect of glutathione on the
chemiluminescence signal of the oxidation of luminol by sodium periodate in basic solution.
The influence of chemical and manifold variables on the sensitivity was studied. At the
optimized conditions, the linear range for the determination of glutathione was 1.0× 10− 8 to
1.0× 10− 5molL− 1 with the detection limit (3σ) of 8× 10− 9molL− 1. The relative standard ...