Authors: Ali A Ensafi, Fatemeh Doozandeh, Ali R Allafchian

Publication date: 2010/12

Journal name: Journal of the Brazilian Chemical Society

Volume: 21

Pages: 2246-2253

Publisher: Brazilian Chemical Society

The construction, evaluation and analytical application of a new potentiometric sensor for
the determination of betahistine are described. The membrane electrode acts based on
betahistine-tetraphenylborate ion-exchangers as electroactive material. This electrode has a
linear dynamic range between 1.0 x 10-6-1.0 x 10-1 mol L-1 betahistine with a Nernstian
slope of (29.74±1.47) mV decade-1 and a detection limit of 5.8 x 10-7 mol L-1. The
potentiometric response is independent of the pH of the solution in the pH range of 4.27 to ...