Highly sensitive voltammetric sensor based on catechol-derivative-multiwall carbon nanotubes for the catalytic determination of captopril in patient human urine samples

Authors: Ali A Ensafi, Hassan Karimi-Maleh, Shadpour Mallakpour, B Rezaei

Publication date: 2011/10/15

Journal name: Colloids and Surfaces B: Biointerfaces

Volume: 87

Pages: 480-488

Publisher: Elsevier

A new catechol-derivative compound, N-(3, 4-dihydroxyphenethyl)-3, 5-dinitrobenzamide,
was synthesized and used to construct a modified-carbon nanotubes paste electrode. The
electro-oxidation of captopril at the surface of the modified electrode was studied using
cyclic voltammetry, chronoamperometry, and electrochemical impedance spectroscopy.
Under the optimized conditions, the differential pulse voltammetric peak current of captopril
increased linearly with captopril concentration in the ranges of 6.4× 10− 8 to 3.2× 10− ...