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Detection of DNA damage induced by chromium/glutathione/H< sub> 2</sub> O< sub> 2</sub> system at MWCNTs-poly (diallyldimethylammonium chloride) modified pencil graphite electrode using methylene blue as an electroactive probe

Authors: Ali A Ensafi, Maryam Amini, Behzad Rezaei
Publication date: 2012/12/13
Journal name: Sensors and Actuators B: Chemical
Publisher: Elsevier
A new electrochemical biosensor for direct detection of DNA damage is presented by
chromium/glutathione/H2O2 system using methylene blue (MB) as an electroactive probe. In
this work, MWCNTs modified poly (diallyldimethylammonium chloride), MWCNTs–PDDA,
nanoparticles were prepared. Then, a pencil graphite electrode (PGE) was modified with
MWCNTs–PDDA nanoparticles. Finally, a double strain DNA (ds-DNA) was assembled on
the surface of the modified electrode. To detect the DNA damage, the modified electrode ...


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