Polydopamine-modified MWCNTs-glassy Carbon Electrode, a Selective Electrochemical Morphine Sensor

M. Sabeti, Ali A. Ensafi, B. Rezaei

Electroanalysis 2021, 33, 2286 – 2295, https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.100...

Abstract: An electrochemical sensor based on a glassy carbon electrode was prepared using f-MWCNTs and polydopamine. Several techniques were used to investigate the surface features. Voltammetric techniques were used to evaluate the electrocatalyst efficiency, and it was used for morphine determination using differential pulse voltammetry. Different parameters affecting the method‘s sensitivity and selectivity were optimized. The linear dynamic range was 0.075–75.0 μM with a detection limit of 0.06 μM morphine. Also, the method‘s selectivity was tested, which was proved to be satisfactory. Finally, the sensor was successfully used for morphine determination in human plasma and urine samples with acceptable results.

Keywords: Morphine · MWCNTs · Polydopamine · Electrochemical sensor